ViziLite Plus
Now that said, my dentist is not an ambulance-chaser (although there's one guy in the office who is the "TMJ expert" and I won't let him near me). My dentist had, in fact, just returned from Tanzania yesterday where he was doing dentistry as a mission. He's generally a decent guy.
So today I was faced with a choice that I think is on the ethical borderline: whether to be screened for oral cancer using something called ViziLite Plus. This is a rinse that you use, and then they peer into your mouth with ViziLite, a "specially designed light technology." This technology can reveal cancer before it is visible in ordinary light.
I was first shown an "informational video," which was actually a brief Fox "news" story about oral cancer and ViziLite, focusing on a 27-year-old woman who died from oral cancer. The "doctor" narrating the story offered some facts which are also available in the ViziLite brochure:
* 25% of oral cancers occur in people who don't smoke and have no other lifestyle risk factors.
* The American Cancer Society estimates a 5.5% increase in new cases of oral cancer and a 1.5% increase in deaths associated with oral cancer.
* When oral cancer is found early, treatment is 90% successful, otherwise the outlook is grim (I can't remember how grim she said in the "news" story, that info is not in the brochure, 50% five year survival rate?).
* Someone dies from oral cancer every hour.
Finally, the "doctor" shared that the test was some percent effective (90%? 98%?), which meant that you might have to undergo further tests because of a false positive, but "hey, better safe than sorry, right?" She also noted that most insurance won't cover the cost of the test (which is $45 at my dentist's office).
My hygienist came in and asked me if I wanted the screening. My hygienist and her husband have both had cancer, so I didn't want to have a discussion about the screening or cancer in general. I simply asked a question that wasn't answered on the video, "What percentage of the population actually gets oral cancer?"
She had no idea. "But I do know that 25% of the people who get oral cancer have no lifestyle risk factors." (In fact, in the pamphlet I was given, you can fall into three categories: increased risk, high risk, and highest risk. My question is, increased from what? Is there just "risk"?)
I told her that a quarter of an infinitesimal chance was pretty small, and I'd have to research the chances of contracting oral cancer before I made a decision. I've had enough screenings that are paid for by my insurance, such as mammography and colonoscopy, to know that a false positive is no picnic. Three times in my life I've waited for a result that might be cancer, and it never has been. In all three cases, I had actual symptoms. I appreciate that these screenings exist, but in some cases I question the value of "better safe than sorry." I don't like waste, I don't like false positives (which lead to more tests), and the dentist has eroded my trust with his ads for veneers and whitening and his shady cancer-screening scare tactic FOX "news" clip. In fact, many doctors have eroded my trust with their "I have a hammer, you look like a nail" philosophy. Doctors are what they are -- we must be realistic about this fact. You are a matching game to them -- match the symptoms to the prescription or procedure, not a complicated human puzzle to be solved and treated holistically.
So I decided to try to find the chances of contracting oral cancer on my own.
First of all, infection with HPV16/18 is a risk factor, which is why, they're speculating, more young people are contracting oral cancer. Is infection with HPV considered a lifestyle risk factor? The brochure is not clear. My gynecologist just tested me for HPV infection and I've never been exposed. Does that mean that I'm less likely to be one of the 25% of oral cancer sufferers who doesn't have lifestyle risk factors? It's not clear, but I'm definitely not a smoker, drinker, or tobacco chewer.
The oral cancer foundation* says that more than 34,000 Americans will be diagnosed with oral or pharyngeal cancer this year. (Does this test screen for pharyngeal cancer? The pamphlet says the dentist examines your mouth, not your pharynx.)
According to the National Cancer Institute, there will be 22,900 new cases diagnosed this year and 5,390 deaths. That's not one an hour, so I'm not sure what the discrepancy is. Perhaps one includes the pharyngeal and the other doesn't, but since the screening doesn't seem to screen for pharyngeal cancer, it doesn't seem right to use those statistics in the pamphlet. Clicking on a statistics link, the National Cancer Institute estimates 35,310 people will contract oral or pharyngeal cancer, with 7,590 deaths. (Still not one per hour. I can't shake the image of the ViziLite Plus people conking a few oral cancer victims on the head to round out the numbers to a nice neat one per hour.)
The statistics page also offers this: 0.74% of men will develop cancer of the oral cavity and pharynx between their 50th and 70th birthdays compared to 0.25% for women.
Now a quarter of that .25% will have no lifestyle risk factors, so that's .0625% of women contracting this cancer between the ages of 50 and 70. (I assume the risk is lower for women younger than that.) And what about women who have no lifestyle risk factors and don't have HPV? Not clear.
.58% of all women will develop ovarian cancer during that same age range,
5.62% of all women will develop breast cancer,
1.58% colorectal,
2.33% lung,
just for some similar statistics on other cancers. I read on one of these sites that it's the sixth-most prevalent cancer, but again, that includes the 75% of diagnosed sufferers with lifestyle risk factors.
So is it worth the screening? That depends on how much $45 means to you (or whatever your dentist charges) vs. how you will react to a positive result (false or otherwise) and what kind of further tests will be done (I'm guessing biospy). If the false positive rate is 2% (I have no idea what it is), I'm more likely to have a false positive than a true positive, and you most likely are getting a piece of your mouth sliced off for nothing.
I don't object to the screening, just the general lack of information and the scare tactics used to push it.
*Oh, say, guess who one of the corporate partners/sponsors for this ".org" is? Zila Pharmaceuticals, Inc., the makers of ViziLite Plus.
